Overweening Generalist

Showing posts with label philosophy of science. Show all posts
Showing posts with label philosophy of science. Show all posts

Sunday, March 1, 2015

A Haunting Frame For Generalist Intellectual Types in 2015

The optimist says, "The glass is half full."
The pessimist says, "The glass is half empty."
The rationalist says, "The glass is twice as big as it needs to be."

A general problem for insatiable readers and writers of journal articles, non-fiction books, novels, poetry, sociologies of science, histories of ideas, essays on arts, rants and diatribes by marginalized figures, economic ideologies, radical thinkers, etc: Let's let this dude sum it up for me:

"It requires in these times much more intellect to marshal so much greater a stock of ideas and observations...Those who should be guides for the rest, see too many sides to every question. They hear so much said, and find that so much can be said, about everything, that they feel no assurance about anything."

This is John Stuart Mill, in his diary, 1854. And for Robert Anton Wilson fans, how many Jesuses ago was this? 32? 64? 256? Oh wait: forgot to carry the three....several thousand J ago, arithmetically in fact.

                                         Emile Zola, apparently in self-portrait, trying to
                                         come off as a magician of some sort?

It's fairly well-known that, for a long time, intellectuals on the "humanities" side have wanted to foment revolution, and most-times a non-violent one. Some on the technical intelligentsia side have too. And the "intellectual" as well-known category traces only back, according to a popular intellectual riff, to the Dreyfus Affair. Emile Zola - a damned novelist so what the hell gives him the right to question?! - led the charge against the French military, and was hounded out of the country. But Zola and his fellow "Dreyfusards" were right: Dreyfus was innocent, and being persecuted largely for being a Jew. This story was resolved only 109 years ago.

And while the technical intelligentsia - specialist intellectuals in the physical sciences, to be brief - are a quite young group, maybe only 140 years old, the Humanist intellectuals go back perhaps 3000 years, if you include religious radicals, or just Old Men Who'd Read Everything.

The Haunting Frame
The dream of making a war-less, border-less and much more equitable and human political state of affairs perhaps had a window, briefly open, now closed. How so?

Well, for one thing, the class of State-supported scientific intellectuals have won. Oh sure, the economy is bad enough that even their newly minted PhDs are having trouble finding work, but it's nothing like what's going on for the Humanities PhDs. (Bing "adjunct professors") Moreover, another quote to suit my dire thesis:

"In this tremendous contrast with previous revolutions one fact is reflected. Before these latter years, counterrevolution usually depended on the support of reactionary powers, which were technically and intellectually inferior to the forces of revolution. This has changed with the advent of fascism. Now, every revolution is likely to meet the attack of the most modern, the most efficient, most ruthless machinery yet in existence. It means that the age of revolutions free to evolve according to their own laws is over."

That's Franz Borkenau, from his 1938 study of the Spanish Civil War. He's talking the military and police state apparatus, which will, it seems, always protect the interests of what's now called "the 1%." He had no idea about digital technology or the NSA, much less television. Even the Stasi were far in the offing.

What Were the Functions of Generalist Intellects?
I've seen a lot of answers, from the New York intellectuals themselves talking about their own powers and knowledges. I've read the lamentations in Russell Jacoby's book The Last Intellectuals. I've read just about everything Chomsky has to say about how his colleagues have used their knowledge and privilege to throw in their lot with the Owners of the country. (In this he's a lot like what Julien Benda said about his own class - in 1927! - in his The Treason of the Intellectuals. For those who see the irony here and like to savor it, please do so.) There is no end of books on intellectuals, if only because this "New Class" is so zealously protective of its own rights and privileges.

Whether from New York or London or Paris, or Hollywood's Hitler-inspired Jewish intellectual diaspora, or wherever else, a literate public saw how ideas hung together, how stylish sentences about important matters could revivify the mind, how discrimination among ideas could take place, how a writer could make something that you thought was not interesting was au contraire: quite a kick. Via wide-ranging intellect, the idea of a vibrant and informed popular culture was possible.

I think this may be all over. Not that there aren't still overweening weirdos who live for this stuff. But this one has to get All This off his chest. Possibly because I hope I'm wrong. Maybe because it's some sort of misery loving company thing. Or, you just like reading bookish jagoffs throw their erudite hissy fits; my misery loves your company. Could be I'm in a 30 Year Funk. Maybe I'm like the guy who just realized he got rooked by mega-unwisely investing in a chain of Foto-Mat booths, nationwide, in this year Our Lady of Eris, 2015.

It could be that, via some sort of magickal working, I confess my haunting frame here - many of you may be well ahead of me on this, I know, I know - so that it will ameliorate things and somehow cause them to go in the opposite direction. But this last "maybe"? I don't feel it. I know the words but not the tune. It feels flat. More's the pity.

Know Thy Enemy/Due Diligence
For me, it was a few solid years of feverish reading of the rise of Public Relations, and tangentially related areas. Such as the 1947 National Security State, which has never left us, only gets stronger, a Behemoth of untold proportions, one of its favorite moves being to make Itself invisible to almost everyone, all the while suctioning the sustenance from its own citizenry.

The signal fact about public relations experts - who Antonio Gramsci called "masters of legitimation" - is that they were so out in the open about what they did and why. Now? Not so much. But check out Harold Lasswell - or is it Edward Bernays? my notes are old and unclear; I had no idea I'd be blogging, and indeed, Internet wasn't really a Thing when I crashed on PR - anyway:

"The spread of schooling did not release the masses from ignorance and superstition but altered the nature of both and compelled a new technique of control, largely through propaganda..." He goes on to say this is the best means of controlling the proles because it's cheaper than bribery or outright violence.

It took a long time for me to not be struck by how arrogant these Mandarin intellectual officials were, or how gleefully subservient they were to the Captains of Industry and War. (And the National Association of Manufacturers and the US Chamber of Commerce, et.al) I was stunned by the disparity between what experts in legitimation for the Owners of the country think versus  all the patriotic "we're all Americans" "in this together" and "freedom" and "democracy"hokum I got in my own indoctrination camps (9AM to 3PM public schooling, minimum of 12 years served).

Some of these pricks just gave it all away. You think Lasswell (Bernays?) was crass, check out one of the fathers of the Neo Conservative movement, Irving Kristol:

"It has always been assumed that as the United States became more managerial, its power more imperial, and its population more sophisticated, the intellectuals would move inexorably closer to the seats of authority -- would, perhaps, even be incorporated en masse into a kind of 'power elite.'" (origin of quote unknown to me due to bad note-taking, but found again in George Scialabba's What Are Intellectuals Good For?, p.7)

If I had to pick two of the most egregious of these legitimators of State power today in Unistat, David Brooks and Thomas Friedman could easily lead the pacifist writer of this blogspew to punch either in the mouth, were I to come to within fist-shot of either. Talk about "treason"...

What intellectual on our side is seen talking about political ideas on the teevee in Unistat? Lemme see...Glenn Greenwald. (And you can only guess what multi-millionaire former head of the taxpayer-funded NSA Keith Alexander thinks about Greenwald: he ought not exist. Let's not even bring up Edward Snowden. Anyone got anyone I missed?)

Yea, But The Science Guys Can Come Around, Right?
Not likely. That's not to say there aren't physicists, chemists, biologists and engineers on the side of the huddled masses yearning to be free, or at least make their rent. Clearly there are many out there. But they still want their jobs. They're addicted to solving abstruse technical problems, then heading home to the spouse and kids. Compared to the average certified Humanities person, the physical science guys are apolitical. (In general.)

There's a heady literature (if you dig and have a library card) about the political commitments among the technical intelligentsia. Most of the best ones are about the morality of their commitments. My favorite among the minority of books that question those commitments from a libertarian position is a guerrilla ontological book, jocoserious, satirical and pissed: The New Inquisition: Irrational Rationalism and The Citadel of Science, by Robert Anton Wilson. RAW has all the generalist chops of any New York intellectual, but rarely did one of that storied group take on the scientific elite. A golden passage here, and realize the book was published in 1986, but keep in mind Unistat's straddling of the globe with its military, and why Islamic militants are at such wit's end of desperation they're cutting off heads of journalists, knowing a drone could likely obliterate them with zero foreknowledge tomorrow afternoon, after having a piece of baklava:

"The late J.B. Priestly often animadverted among what he called The Citadel - the scientific-technologic elite which both supports and is supported by our military-industrial alpha males. The Citadel, in most countries, gets millions of pounds for every twopence doled out to the humanities, the social studies or the arts; it devotes most of its time and intellect to the task, as Bucky Fuller used to say, of delivering more and more explosive power over greater and greater distances over shorter and shorter times to kill more and more people. For this reason, The Citadel increasingly frightens most of us and there is a vast,  somewhat incoherent rebellion against it all around the world. The rebellion takes the form, most of the time, of return to some earlier philosophy or reality tunnel (hello ISIS and al-Qaeda! - OG), although within the scientific community there is also a rebellion which is seeking a new reality-tunnel, which is usually called The New Paradigm." - pp.20-21 of my tattered, pages-falling-out copy



RAW goes on to say Citadel personnel are intensely territorial, including in ideology, and they're proud of their atheism. He's appalled by death-centered nature of this well-educated group, but makes it clear his book is not an attack on the Citadel's moral grounds, but rather its violations of what he sees as the right of free speech and for every scientist to report any finding, even if it's in violation of the current paradigm(s). He particularly loathes the inquisitorial doings of the Citadel's ideological protectors in persecuting scientific heresy, as this simply should not take place in a supposed Free Society. Although RAW uses a rhetoric that at times seems outlandish in The New Inquisition, I think his thesis is very strong and ought be heeded. The academic version of his approach to the philosophy and history of science would be found in Paul Feyerabend, in a work such as Against Method, and possibly in Imre Lakatos's work. Bruno Latour's application of ethnomethodological-like inquiry to practices in actual scientific labs seems to bolster RAW's more Swiftian/Nietzschean/Fortean rhetorics. I also see a family resemblance in Jean-Francois Lyotard's The Postmodern Condition: A Report on Knowledge.

However, I don't need a weatherman to know blah blah blah, and I guess we will just have to see if "Reality" can deal us a surprisingly good hand. Meanwhile, we do what we can.

Whither the University in General?
This deserves a few other blogspews of its own, but student debt is now well over $1,000,000,000,000 and mounting fast, and not only do young people "graduate" with a "degree" but they seem to not be able to think all that well for themselves. But then there aren't any jobs for them anyway. Meanwhile the highest paid public servant in most states is the head football coach, and that entire system stinks to high heaven. Go ahead, lift the lid and take a whiff. It's sulphurous-rotten and the older, comfy alumni say "Let's go all the way this year!" Their best players don't get educations and barely have enough to eat. If they're lucky they won't suffer brain damage by the age of 45 from too many violent blows to their inadequately helmeted heads. And undergraduate costs have vastly exceeded inflation (gee...why?), and your freshman is largely being taught by "adjunct" professors who make less take-home pay than a head manager at Burger King. Try to tell me how this is sustainable. Meanwhile, Obama seems to think  it's of the utmost importance to keep sausage-grinding-out "college graduates." So they can...monitor robots?

Well, The Citadel does need a plentiful supply of STEM students. Fuck the Humanities bastards, with their questioning of the political economy and values and all that.

It should get pretty interesting. I can't help but imagine the increasing numbers of very bright, hyper-educated Humanities types, and their degrees and their debt and the increasingly fucked job market. Will they get political knowing the NSA might be tracking their every move?

The entirety of scenario(s) above constitute a mere model, or frame. Since I'm not a modeltheist, I don't think I'm presenting "the Truth" here. I merely affirm it might have some weight and heft, and that I don't exactly consider the model as anything close to a felicitous state of affairs. I've tried working myself into a lather about the cup being twice as big as it needs to be, but it's not taking.

I will leave us there, to escape back into my comic books.

                                    image by Bobby Campbell    

Thursday, December 13, 2012

Free Radicals, by Michael Brooks

I never tire of contemplating how Copernicus and his co-conspirators gave us a convincing heliocentric view, and how that ricocheted and echoed down through time and changed the way individuals conceived of themselves in the cosmos. To knock the geocentric view out of the picture was quite the coup, eh? Then Darwin (and aye: Alfred Russell Wallace and scads of others) carries off an even bigger move: we're part of a long line of mammals; we're not God's Special Kids. Einstein and Hubble and many others made us understand that we're only part of a so-what solar system, one of quintillions (at least!) that exist. (Hubble space telescope sees a tribe of galaxies from the dawn of the universe.)

And yet some human egos need to resist these insults. To me, these new models constitute knowledges that are compliments to human ingenuity, having the added bonus of being "true."

Copernicus called nature "God's temple," and said we can know God through studying Nature...which got the Vatican to put his Copernicus's book on the Index. We do not know what, if any, drugs Copernicus took, but I do see him as a mystical weirdo, one of the guys on my team.



Darwin seemed very upset that he was upsetting the God-fearing. He had a lot of physical ailments, but he published his books anyway, and I continue to be staggered by his accomplishments. He followed up on some Wild Ideas put forth by thinkers in the immediate previous generations, ideas from disciplines not his own, like geology. And he persisted, despite sicknesses, as if possessed, because the Wild Ideas were interesting and might allow him to midwife some Wild Child of his own. One of my favorite sociologists of knowledge, Randall Collins, makes a very persuasive case that the most valuable thing an intellectual can do is to open up new spaces for other intellectuals to think in. And what a space Darwin opened up! Jaw-dropping...

                                                        Charles Darwin

Einstein seems sorta embarrassed by how he developed his world-shattering ideas: daydreaming, goofing off, tinkering around with images. He had mystical ideas about how Nature worked, but the his math wasn't up to snuff to prove them. As Michael Brooks writes in his recent book, Free Radicals: The Secret Anarchy of Science, "His papers are riddled with errors and convenient omissions - though they were lazy fudges rather than, as with Newton, deliberate frauds. Einstein repeatedly failed to take account of known facts when formulating his ideas." (p.7) Supposedly Einstein once said, "The secret to creativity is knowing how to hide your sources." His inspirations had no traceable source, hence Brooks's term for Einstein's animus: "mystical." It was clear to Einstein that working on the most interesting unsolved problems in physics could not be done logically, deductively, step-by-step: this would be beyond human capacity. No, he used Something Else...And one of the results was the ending of WWII.

Well, Brooks's book wonderfully extensionalizes/elaborates on Paul Feyerabend's main thesis: that "anything goes" in science. It's the best on this subject I've seen yet. I'd like to say that Feyerabend (mentioned in the book) would be pleased, but you never really know with Feyerabend.

Another Brief Riff on Perspective: Science as a "Brand," 1945-Now
Brooks says his book is about "the humanity of scientists - and what that really means." And he juxtaposes this with a narrative foisted upon almost all of us: the scientists are basically slightly less caricatured versions of Mr.Spock, from Star Trek. Brooks says this is a "cover-up" that's been wildly successful "because even the scientists haven't understood what has been going on."

Here's the Science brand after 1945: It's "logical, responsible, trustworthy, predictable, dependable, gentlemanly, straight, boring, unexciting, objective, rational. Not in thrall to passions or emotion. A safe pair of hands. In summary: inhuman." (p.2) Brooks elaborates on this at length, and it's a slam-dunk to me, an inveterate reader of dissentual data about this Science brand, which I smelled as bovine excreta at age 17. But it's the details and solid research, coupled with an investigative journalist's style - Brooks has a PhD in quantum physics - coupled with an enthusiasm to shine light on the cover-up, that makes the Brooks book so eminently readable.

Almost every fantastic breakthrough in science does not meet the "scientific method" narrative they still brainwash kids with in the schools.

To those interested in Buckminster Fuller's thesis about scientists as "Wizards" that the Machiavellian Owners of the World bought off: there's much here to build on Fuller's argument. (I'm mostly referring to Fuller's criminally underappreciated GRUNCH of Giants.) Brooks quotes Michael Schrage in referring to the bankers/corporations/energy moguls after WWII, when physicists were seen as the "Merlins of the Cold War...their wizardry could tip the balance of the superpowers in the twinkling of a quark."

Q: If the Scientist-as-Spock story is hooey, then what does go on?
A: Dreaming, cheating, mania, drugs, daring self-experimentation, pranks, and High Weirdness in general.

But let me return to perspective.

                                       "Earthrise," taken xmas eve, 1968, Apollo 8

Stewart Brand on LSD in San Francisco
In the mid-1960s, Brand, who paid attention to seemingly everything that would later change the world - was high on acid on a gravel-covered roof in the beatnik-y North Beach district of San Francisco. He was thinking about space flight and how astronauts had recently gotten glimpses of Earth from space: a new perspective. Then he remembered hearing Buckminster Fuller give a talk in which he thought a major flaw in humanity's assumption about itself that has led us to a possible brink was that, even though most of us "know" the world is round, we don't really conceptualize of our planet that way. We tend to conceive of the world as flat, and if we could only carry around with us the image of "a round ball, isolated in space, an island in an inhospitable cosmos, perspectives would change." And Brand, on LSD, became transfixed on allowing us all to see a picture, a photo of the Earth. He worked tirelessly, like a campaigner, writing NASA, getting college kids all riled up, writing the UN, the Soviets, members of Congress. He started in February of 1966, and by the end of 1967, photos of from Apollo 8 - one taken by William Anders, and called "the most influential environmental photograph ever taken,"by Galen Rowell in The 100 Greatest Photographs That Changed The World, was perfect for Brand's purposes. (Brooks, pp.15-17)

Carl Sagan's "Pale Blue Dot"
The words are from Sagan, watch this 3 1/2 minute video. Is this perspectival-feeling "olde news" to you? Or do you still feel it? Are we jaded? Does anything shift inside you? Or do you remember when it did, but now you're concerned with the multiverse or dark matter? Does this seem "cheesy"to you? Or does it make you melt, emotionally? What does it do to your sense of "self"?

Oh, now we can access via library DVDs, the science channels on TV, other amazing cosmological schtuff on You Tube...other planets, galaxies, taxonomies of galaxies, etc. But the pale blue dot was what Bucky Fuller wanted us to feel so we'd start to think we all live on this spaceship planet together, and do we really want to make it an armed madhouse? Michael Brooks makes a good argument that we  might never have gotten this perspective without radical, anarchic thinkers.

                                                        Dr. Lester Grinspoon

Carl Sagan was a bigtime pothead. He was good friends with Harvard MD Lester Grinspoon, who was a pioneer in medical pot. Brooks relates how Sagan liked the creative insights cannabis gave him, and tried to capture these by tape recording them so he'd be able to access them and take these ideas seriously the next day, when his buzz was gone and he needed to write. Dig this bit from Sagan via Brooks:

"If I find in the morning a message from myself the night before informing me that there is a world around us which we barely sense, or that we can become one with the universe, or even that certain politicians are desperately frightened men, I may tend to disbelieve; but when I'm high I know about this disbelief. And so I have a tape in which I exhort myself to take such remarks seriously. I say, 'Listen closely you sonofabitch in the morning! This stuff is real!'." (p.246)

Brooks's Free Radicals tells of the somewhat likelihood of Francis Crick's LSD use, and how it may have helped Watson and himself to discover the structure of DNA. Kary Mullis's LSD use is now-legendary, and he thinks it was a valuable asset in his discovery of the polymerase chain reaction technique, for which he won a Nobel Prize. Richard Feynman's pot smoking and LSD use is mentioned, as is William James's experiments with nitrous oxide.

But the true value of Brooks's wonderful little book is that he has quite thoroughly dismantled the "brand" of Science being done by slightly human Mr. Spock-types we were all taught; he gives a withering number of examples in a breezy prose that the business of making scientific breakthroughs is anything but clean and orderly and rational. It's thoroughly, gloriously, anarchic.

A 90-second bit with Michael Brooks:





Saturday, August 4, 2012

John P. Ioannidis and Reading the Latest Dispatches From the World of Science, Featuring Jonah Lehrer

In 1905 - stop me if you've heard this one - a young Swiss patent clerk published three papers that have shaken the world of physics ever since. We have not thought about little things like matter, space and time the same way since Einstein published in Annalen der Physic, in his Wunderjahr 1905, papers that proved to be paradigm-shattering and which addressed puzzling anomalies surrounding the photoelectric effect and Brownian Motion. Then Einstein added a little something called special relativity.

In 2005, an epidemiologist and medical statistician published two papers that had a similar effect in medical research. His name? John P. Ioannidis. (Say "yo-NEE-deez") He was a math prodigy and, after studying rare diseases, became interested in the problem of solid research that backed almost all of the taken-for-granted truths that your doctor and most medical researchers were working with. At first he thought he would take the rather paltry and shoddy studies that formed the basis of sound medical practice, then perform his speciality: a critical analysis of the founding papers, do a meta-analysis, and shore up and legitimize what had been a bit non-rigorous and sloppy for a body of practice that was so basic to our understandings of the best modes of treatment.

And...just...oh boy...

This was in the 1990s. Ioannidis, in his research, found that about 90% of what doctors believe and what they tell their patients, what drugs they prescribe, was seriously flawed. The research that supposedly legitimized the dogma in most of our doctors' heads was riddled with mistakes.

                             John P. Ioannidis, hero of this blog-spew, underrated thinker?

Brief Digression
I admit it: I read probably 100 articles a week on little scientific findings that sound..."interesting." I love Science Daily! There are about six or eight other science sites I read regularly, and I'm interested in  physics, chemistry, cosmology, medical findings, neurobiology, social psychology, genetics, archaeology, evolutionary studies, on and on, und so weiter. And I link to those in the OG, as for instance, earlier articles on the obesity problem, which is serious to me. But there's reason to believe, given what John P. Ioannidis has found, to read those studies with far more than a grain of salt. Rather read with something in mind between a dull news article about some crime that was committed...and fiction. Why? Read on.

Ioannidis and His Two Papers of 2005
One was published in PLoS and had a wonderfully provocative title: "Why Most Published Research Findings Are False," and was a rigorous mathematical proof that, summarized by David H. Freedman, who wrote the best journalistic piece I've seen on Ioannidis (HERE, and highly recommended you read it three times over the course of a year), as "Simply put, if you're attracted to ideas that have a good chance of being wrong, and if you're motivated to prove them right, and if you have a little wiggle room in how you assemble the evidence, you'll probably succeed in proving wrong theories right." This applies to medical research, but many researchers in other fields have taken note.

Another way of summarizing Ioannidis's meta-research here (the PLoS paper their most downloaded one ever, and heavily cited by others) could be like this:
1. Assume modest levels of researcher bias and add to that:
2. typically imperfect research techniques, and then add to that:
3. the human tendency (well-known) to focus on exciting rather than highly plausible theories, and it all adds up to:
4. VOILA!: researchers will come up with wrong findings most of the time

Isn't this sorta galling, freaky stuff? Or is it just me?

[I consider David H. Freedman one of our very best Expertologists, and I just now remembered that I wrote about him and his book HERE.]

Also in 2005, Ioannidis published, in Journal of the American Medical Association (JAMA), a paper that tested the idea that, sure, there's a lot of bad studies, but the larger social world of doctors and medical researchers will read these flawed studies and be able to identify them; the flawed stuff will get weeded out. As you may have guessed, this was not found to be true.

Ioannidis picked 49 of the most highly regarded research findings over the previous 13 years. These were the most widely cited articles in the best peer-reviewed journals. These papers had to do with hormone replacement therapy for menopausal women, vitamin E to stave off heart disease, the use of coronary stents, and daily low-dose aspirin for keeping the arteries unclogged, etc.

41% of these studies were shown to have major flaws. Physicians and researchers do not know how to see through dubious research findings. Or there's a herd mentality among medical professionals. Or some would rather not know. Or possibly all of the above and Something Else.

A Few Upshots From All of This
Ioannidis shows there are routinely problems at any and every step of the research process, and they have to do with conception and hypotheses, research techniques and other methodological problems, conclusions, conflicts of interest, the human desire to make a breakthrough, the human desire to publish to gain academic standing, the need to feel part of a larger research group by supporting their findings, and the politics of peer-review and how journals decide to accept or reject certain papers. Among other things. Like the common obsession of winning a big research grant, often from Big Pharma.

On top of all that, the field seems resistant to change what it already "knows." Sorta like the tuberculosis out there now, that's resistant to antibiotics because those antibiotics were too over-prescribed? (Hold on, that may be a Bad Analogy...)

Regarding obesity studies, Ioannidis says "ignore them all." Why? Because they're seriously flawed. Some studies found fat people live longer than expected, and were just as healthy as the non-fat. Why? The problem of bio-markers: they tell us something, but not the entire picture, and they don't take into account very many other interactions within the body. We may be spending far too much in the wrong places. What about using Vitamins A, D, and E? Forget those studies also, says Ioannidis. What about whether we should eat more fat or carbs? Forget it, says John P. Read the David Freedman article from The Atlantic that I linked to above for Ioannidis' reasons why these studies are to be ignored.

Then...then...then...if there's so much bad research done in the medical field, what about our health, as a society? Ioannidis answers: "That we're not routinely made seriously ill by this shortfall [of truly evidence-based medicine] he argues, is due largely to the fact that most medical interventions and advice don't address life-and-death situations, but rather aim to leave us marginally healthier or less healthy."

Ioannidis says bad ideas spread like an epidemic, "They're spreading it to other researchers through journals," says Ioannidis, who Freedman says looks "like Giancarlo Giannini with a bit of Mr. Bean."

How were Ioannidis's two bombshell papers received by the medical community? Very well. People seemed relieved. He was attacking general mistakes, and so every researcher could say to himself, maybe something like, "Yep, this stuff goes on a lot, and it's a problem. My colleagues need to be very careful..." It's not you who conducts bad research; it's other people.

Interestingly, in 1989, two Economists, Kevin Lang and Brad DeLong, published a meta-study of economic dogma and research and what they found was very much like what Ioannidis found: basic assumptions that formed the working models of almost all economists were found to be seriously flawed. However, the field of Economics has not embraced their research. There seems to be a profound lot of significance here about who we are, but I will leave that to my Dear Readers.

Here's Jonah Lehrer on video, for 30 seconds, explaining why he became a journalist:


Jonah Lehrer on This Stuff
Although I consider David H. Freedman's piece on Ioannidis most excellent journalism, Jonah Lehrer published a pretty terrific piece around the same time as Freedman, and about roughly similar problems in epistemology and scientific methodology, but for The New Yorker. It's HERE, and I was enchanted by the many examples of fascinating research Lehrer strings together. It's very entertaining, or at least I thought it was/is. Lehrer is trying to tease out a problem in science: that "the truth wears off," the name of his piece. The idea of verbal overshadowing and how it related to J.B. Rhine's studies in ESP was fascinating. One researcher's term, "cosmic habituation," reminded me of a fascinating outlaw biologist, Rupert Sheldrake, whose outre ideas about morphogenetic fields has not exactly been embraced by the larger Biology community.

Jonah quotes Ioannidis here, and many others. Irony-lovers: note the last paragraph of Lehrer's piece, where he writes, "Because these ideas seem true..." But I don't want to jump on Jonah here. He's gotta be reeling right now, the 31 year old fallen genius who fucked up royally. I am not one of those given to schadenfreude in this instance.

But read Lehrer's piece. Are you suspect of his research, now that you know he'd been outed as a fabricator of some sort? I find that I mostly believe what he's writing here. I particularly like what Jonah has to say about the "decline effect" in science, and I'll quote him here before giving Ioannidis the last say:

Jonah Lehrer: "The decline effect is troubling because it reminds us how difficult it is to prove anything. We like to pretend that our experiments define the truth for us. But that's often not the case. Just because an idea is true doesn't mean it can be proved. And just because an idea can be proved doesn't mean it's true. When experiments are done, we still have to choose what to believe."

Or, as Paul Feyerabend might've said, "Anything goes." Keep delving into the inner machinations of scientific research and it looks more and more like anarchy to us (well, I'll speak for myself and Feyerabend), and a lot less like the way Francis Bacon envisioned it.

I leave us with this quote from Ioannidis, which I find very poignant, hard-nosed, and revelatory of how rare and truly special the findings in any scientific field have been that have truly worked to provide major breakthroughs, research - like Einstein's - that led to a new paradigm:

"Science is a noble endeavor, but it's also a low-yield endeavor. I'm not sure that more than a small percentage of medical research is ever likely to lead to major improvements in clinical outcomes and quality of life. We should be comfortable with this fact."

Here's Jonah Lehrer on Charlie Rose, talking about Bob Dylan and creativity. 2 mins:

Here's a 15 minute video in response to Ioannidis's "Most Published Research Findings Are False," and I think it's pretty good in explaining the statistical methodology for determining good research. The narrator - who, to me, sounds very erudite and funny about this stuff - seems to want to stave off the possible reactionaries who already have problems with "science," or as he says, "on the road to science denialism." Sorry for taking so much of your time!